Neurosurgery Clinical Trials

Many of the neurosurgery trials that we conduct at University Hospitals enroll patients who are in the acute stage of their disease or injury. This means that patients are enrolled while they are in the emergency room, intensive care unit, or operating room. You can read about some of these trials below and at For any questions about our current neurosurgery studies, please contact Val Cwiklinski or Natalie Abraham.

REACT: Prevention and treatment of vasospasm with ClazosenTan for patients with aneurysmal subarachnoid hemorrhage

A prospective, multicenter, double-blind, randomized, placebo-controlled, parallel-group, Phase 3 study to assess the efficacy and safety of clazosentan in preventing clinical deterioration due to delayed cerebral ischemia (DCI), in adult subjects with aneurysmal subarachnoid hemorrhage (aSAH)


Assessment of the Embolization of Neurovascular Lesions Using the Penumbra Smart Coil


A Randomised Controlled Study to Evaluate the Efficacy and Safety of Fibrin Sealant, Vapour Heated, Solvent/Detergent Treated (FS VH S/D 500 S-apr) Compared to DuraSeal Dural Sealant as an Adjunct to Sutured Dural Repair in Cranial Surgery

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