Leroy W Matthews Cystic Fibrosis Center

INTERIM DIRECTOR
Kimberly A. McBennett, MD, PhD

ASSOCIATE DIRECTOR
James F. Chmiel, MD, MPH

ADULT PROGRAM DIRECTOR
Kimberly A. McBennett, MD, PhD

ASSOCIATE ADULT PROGRAM DIRECTOR
Steven Strausbaugh, MD

PEDIATRIC PROGRAM DIRECTOR
James F. Chmiel, MD, MPH

KEY CONTACT
Janice Lee, Program Coordinator 216-844-1997

ADDITIONAL CONTACT
Alfreda Eff 216-844-3267

APPOINTMENT LINE
216-844-1997
For hospital transfers, please call 216-844-1111.

Diagnostic Procedures
Sweat testing in Cystic Fibrosis Foundation-accredited laboratory
Nasal epithelial mucosal brushing, curettage and cell culture
Flexible bronchoscopy with bronchoalveolar lavage, mucosal brushing and biopsy
CFTR gene sequencing
Exhaled nitric oxide measurements
Exhaled breath condensate
Esophageal pH monitoring
Multiple breath washout
Microbiology laboratory qualified for CF cultures
Nasal transepithelial potential difference testing
Percutaneous allergy extract skin testing
Polysomnogram and limited channel sleep studies
Pulmonary function testing, including spirometry, plethysmography, impedance oscillometry, bronchoprovocation with cold air, exercise, and methacholine, and infant pulmonary function testing
Arterial blood gas monitoring
Radiographic services including angiography, computerized tomographic, nuclear and magnetic resonance imaging
Sputum induction

Therapies and Services
Specialized respiratory therapy
Advanced interventions (flexible bronchoscopy, thoracic surgery, lung transplantation)
Genetic and prenatal counseling
Comprehensive newborn screening program for cystic fibrosis

Distinguishing Features
One of the first CF centers in the country, active for nearly 60 years
One of the original seven Cystic Fibrosis Therapeutics Development Centers
Designated as a Cystic Fibrosis Foundation Research Development Center
Newly diagnosed patients have an office visit within 24 hours
Highly collaborative team, including pulmonologists, gastroenterologists, psychologists, endocrinologists, dietitians, social workers, nurses and respiratory therapists
Home treatment program
Specialized cystic fibrosis inpatient unit for adults
Highly active in clinical trials for new cystic fibrosis therapies – has been involved in bringing nearly every new medication to market in the past 20 years
Offers typically more than 25 active CF clinical trials at any time
Works closely with basic scientists to conduct translational research
Associated with one of the largest, most established fellowship programs in pediatric pulmonology
Patients and research participants seen at the state-of-the-art KC and Ginny Bryan Pulmonary Diagnostic Center